Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
US5681585A · kind A · utility
250Cited by
46References
25Claims
0Family size
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Key dates
| Filing date | Jun 20, 1996 |
| Grant date | Oct 28, 1997 |
| Priority date | — |
| Expiry date | Jun 20, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/522
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A stabilized solid controlled release dosage form having a coating derived from an aqueous dispersion of ethylcellulose is obtained by overcoating a substrate including a therapeutically active with an aqueous dispersion of ethylcellulose and then curing the coated substrate at a temperature and relative humidity elevated to a suitable level above ambient conditions until the coated dosage form attains a stabilized dissolution profile substantially unaffected by exposure to storage conditions of elevated temperature and/or elevated relative humidity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.