Methods for producing enhanced antigenic shigella bacteria and vaccines comprising same
US5681736A · kind A · utility
12Cited by
1References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 3, 1995 |
| Grant date | Oct 28, 1997 |
| Priority date | — |
| Expiry date | Oct 3, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/975
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods using in vitro processes are disclosed for inducing or enhancing expression of enteric bacterial antigens or virulence factors. The methods, therefore, produce antigenically enhanced enteric bacteria. Also methods for using the antigenically enhanced bacteria are also disclosed, as well as vaccines containing the enteric bacteria. Specifically, a whole enteric bacteria or components thereof are provided by Shigella species. Also there are other enteric bacteria which are useful for the disclosed invention; such as bacterial species and strains belonging to the genera Helicobacter and Campylobacter.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.