Patent · US Expired

Detection system for mutagens that also identifies mutagenic changes

US5681737A · kind A · utility

5Cited by

6References

29Claims

0Family size

Assignee

The Regents of the University of California · US

Inventors

Pauline Gee · Berkeley, US
Dorothy M. Maron · Orinda, US
Bruce Ames · Berkeley, US

Key dates

Filing date	Oct 15, 1993
Grant date	Oct 28, 1997
Priority date	—
Expiry date	Oct 15, 2013

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12R2001/42
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Six sets of Salmonella typhimurium strains are provided, all strains having low spontaneous mutation rates, and each set being sensitive to and diagnostic of one of the six possible base substitutions in DNA. Also provided are methods for making and using these S. typhimurium strains to detect, and establish the type of specific base substitution mutation induced by, mutagenic agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.