Patent · US Expired

Process for the preparation of substituted 2-fluoro-pyrimidines

US5681957A · kind A · utility

12Cited by

3References

10Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Erich Wolters · Neunburg vorm Wald, DE
Guido Steffan · Odenthal, DE
Alexander Klausener · Neunburg vorm Wald, DE

Key dates

Filing date	May 3, 1996
Grant date	Oct 28, 1997
Priority date	—
Expiry date	May 3, 2016

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D239/30
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Unsubstituted or substituted 2-fluoro-pyrimidines can be prepared by reaction of the underlying 2-amino-pyrimidines with diazotization agents, mixtures of HF and H.sub.2 O containing 30-70% by weight of HF, based on the total of HF and H.sub.2 O, serving as reaction medium. The reaction medium can also contain diluents and/or inorganic salts, preferably fluorides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.