Imidazopyridines as pharmaceutical agents

US5684015A · kind A · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Werner Mederski · Zwingenberg, DE
• Matthias Osswald · Stuttgart, DE
• Pierre Schelling · Mühltal, DE
• Klaus-Otto Minck · Ober-Ramstadt, DE
• Dieter Dorsch · Ober-Ramstadt, DE
• Norbert Beier · Reinheim, DE
• Ingeborg Lues · Darmstadt, DE

Key dates

• Filing date: Sep 14, 1995
• Grant date: Nov 4, 1997
• Expiry date: Sep 14, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Described herein are novel imidazopyridine derivatives of the formula I ##STR1## wherein R is ##STR2## and R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as defined in Patent Claim 1, and their salts, which exhibit antagonistic properties towards angiotensin II and can be used for the treatment of hypertension, aldosteronism, cardiac insufficiency and increased intraocular pressure, and of disorders of the central nervous system.