Substituted benzhydrylamines as handles for solid phase peptide synthesis
US5684131A · kind A · utility
1Cited by
1References
12Claims
0Family size
Inventors
Key dates
| Filing date | Jul 5, 1994 |
| Grant date | Nov 4, 1997 |
| Priority date | — |
| Expiry date | Jul 5, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is directed to a novel "handle" for solid phase peptide synthesis. The handles can be converted from a stable form to a labile form, allowing for cleavage of a peptide amide from the support after synthesis under mild conditions, and after deprotection of the amino acid side chains. The handles are based on a substituted benzhydrylamine skeleton.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.