Patent · US Expired

3-aminopyrroles, methods for their synthesis and for their pharmaceutical use

US5684160A · kind A · utility

0Cited by

1References

7Claims

0Family size

Assignee

Arzneimittelwerk Dresden GmbH · DE

Inventors

Peter Scharfenberg · Wuppertal, DE
Jurgen Liebscher · Dresden, DE
Alexander Knoll · Berlin, DE
Aleksej Uschmajew · Berlin, DE
Andreas Rolfs · Berlin, DE
Dieter Lohman · Radebeul, DE
Gottfried Faust · Berlin, DE
Eveline Morgenstern · Berlin, DE

Key dates

Filing date	May 19, 1995
Grant date	Nov 4, 1997
Priority date	—
Expiry date	May 19, 2015

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P29/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention is directed to 3-aminopyrroles of formula I, which are largely new, to methods for the preparation and to their use as medicinal agents and preparations, as well as to anti-convulsive or analgesic preparations containing these 3-aminopyrroles. Disubstituted and monosubstituted amino groups are claimed as 3-amino substituents. The invention pursues the objective of developing largely new 3-aminopyrroles, which have CNS activity, particularly ones which anti-convulsive or analgesic properties, as well as methods for their preparation and their use as medicinal preparations. Pursuant to the invention, the synthesis is carried out by cyclizing open-chain precursors, such as aminoacrylic acid derivative, or by modifying pyrroles.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.