Patent · US Expired

Apparatus and method for cell separation

US5684712A · kind A · utility

44Cited by
42References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 20, 1995
Grant dateNov 4, 1997
Priority date
Expiry dateApr 20, 2015

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/808
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

An improved cell separator is provided that includes apparatus for automatically controlling the cell separation process. Particularly, a plurality of valves are responsive to a data processor assembly for controlling the path of fluid flow through the cell separator. A plurality of sensors are provided for providing sensor signals indicative of the density of fluid flowing through the cell separator. The microprocessor is responsive to the sensor signals for controlling the flow and operation of the cell separator. A parastaltic pump is responsive to the microprocessor assembly for controlling the speed and direction of fluid flow through the system. A stirplate assembly is responsive to a drive signal from the data processor assembly for controllably agitating the contents of a column. The data processor assembly is further responsive to the sensor input to provide the valve control signals and pump control signal to control the concentration of selected cells that are collected. The improved cell separator further includes an improved stirplate assembly having a column with a stirbar rotatably supported therein. The stirbar includes a magnet section and a stem extending outward …

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.