Di-and tri-peptide mimetic compounds for Parkinson's disease
US5686423A · kind A · utility
15Cited by
0References
16Claims
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Assignee
Inventors
Key dates
| Filing date | Feb 16, 1996 |
| Grant date | Nov 11, 1997 |
| Priority date | — |
| Expiry date | Feb 16, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A series of di- and tri-peptide mimetic dopamine prodrugs are synthesized in which D-phenylglycine or D-p-hydroxyphenylglycine is attached as tools for delivery of L-dopa through the intestine via the intestinal dipeptide-mediated carrier transport system. These compounds are found useful as an active ingredient for the treatment of Parkinson's disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.