Patent · US Expired

Endothelin receptor antagonists

US5686481A · kind A · utility

13Cited by
3References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 20, 1995
Grant dateNov 11, 1997
Priority date
Expiry dateJun 20, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D405/06
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Indole derivatives of formula (1) wherein the substituents are defined herein are disclosed. The compounds are useful in methods of antagonizing endothelin receptors, treating hypertension, treating renal failure and treating cerebrovascular disease. Pharmaceutical compositions are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.