Proline derivatives
US5686628A · kind A · utility
14Cited by
5References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 2, 1996 |
| Grant date | Nov 11, 1997 |
| Priority date | — |
| Expiry date | Feb 2, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to particular forms of a novel 1-substituted-N-2-methyl-1-(trifluoroacetyl)propyl!pyrrolidine-2-carboxam ide which are inhibitors of human leukocyte elastase (HLE), also known as human neutrophil elastase (HNE), making them useful whenever such inhibition is desired, such as for research tools in pharmacological, diagnostic and related studies and in the treatment of diseases in mammals in which HLE is implicated. The invention also includes pharmaceutical compositions containing such forms, processes for preparing the forms and intermediates useful in the synthesis of the forms.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.