Compositions and methods for the synthesis of growth hormone receptor and growth hormone binding protein

US5688763A · kind A · utility

Inventors

• R. Glenn Hammonds · Berkeley, US
• David Leung · Mercer Island, US
• Steven A. Spencer · San Mateo, US
• William I. Wood · Hillsborough, US
• Peter Colosi · Alameda, US

Key dates

• Filing date: May 25, 1994
• Grant date: Nov 18, 1997
• Expiry date: May 25, 2014

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Growth hormone receptor and growth hormone binding protein are purified enabling amino acid sequence and DNA isolates coding for growth hormone receptor and growth hormone binding protein and methods of obtaining such DNA are provided, together with expression systems for recombinant production of growth hormone receptor and growth hormone binding protein. Therapeutically useful forms of the growth hormone receptor and growth hormone binding protein and anti-receptor antibodies are described.