Antihypercholesterolemic compounds and related pharmaceutical compositions and methods of use
US5688780A · kind A · utility
2Cited by
4References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 29, 1996 |
| Grant date | Nov 18, 1997 |
| Priority date | — |
| Expiry date | Feb 29, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J71/0042
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel antihypercholesterolemic agents are provided. An exemplary group of compounds has the structural formula (I) ##STR1## wherein R is a C-17 side chain, R.sup.1 is --OH, .dbd.O, or the like, and X and Y are CH, C--OH, C--OCH.sub.3 or C--Z. Methods of using the compound of formula (I) or other novel oxysterol analogs to treat hypercholesterolemia are provided, as are pharmaceutical compositions containing the compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.