Spiroazacyclic derivatives as substance P antagonists
US5688806A · kind A · utility
6Cited by
6References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 12, 1995 |
| Grant date | Nov 18, 1997 |
| Priority date | — |
| Expiry date | Oct 12, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/76
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel spirocyclic piperidine derivatives and related compounds and, specifically, to compounds of the formula ##STR1## wherein X, Z, Y, R.sup.1, R.sup.2, R.sup.3, R.sup.4 and m are as defined in the specification, and to intermediates used in the synthesis of such compounds. The novel compounds of formula I are useful in the treatment of inflammatory and central nervous system disorders, as well as other disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.