Patent · US Expired

Peptide ligands which bind to von willebrand factor

US5688912A · kind A · utility

7Cited by
2References
2Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 22, 1995
Grant dateNov 18, 1997
Priority date—
Expiry dateSep 22, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K14/001
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Peptide ligands which bind to von Willebrand Factor (vWF) are disclosed. These peptides are selected from the group consisting of RLHSFY, RLKSFY, RLNSFY, RLQSFY, RFRSFY, RIRSFY, RVRSFY, RYRSFY, RLRSFY, HLRSFY, and KLRSFY. The preferred peptide ligand has the sequence RVRSFY. A method of using the disclosed peptides to purify vWF comprises binding the peptides to a support, then passing a solution containing vWF over the supports under condition such that the vWF will selectively bind to the peptides, and then eluting the vWF.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.