Preparation of biologically active compounds from substantially pure enantiomers of 2-azabicyclo2.2.1!hept-5-en-one
US5688933A · kind A · utility
46Cited by
2References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 5, 1995 |
| Grant date | Nov 18, 1997 |
| Priority date | — |
| Expiry date | Jun 5, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P41/006
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Lactams of 1-amino-3-carboxylic acid cyclic compounds are provided in enantiomeric form, together with an enantiomer of the corresponding ring-opened amino-acid or ester, by reaction of the racemic lactam with a novel lactamase. The products are useful in the synthesis of chiral carbocyclic nucleotides. The enantiomer is preferably 2-azabicyclo2.2.1!hept-5-en-3-one.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.