Oral immunization with multiple particulate antigen delivery system

US5690938A · kind A · utility

Assignees

• OraVax, Inc. · US
• Natural Environment Research Council · GB

Inventors

• Thomas H. Ermak · Cambridge, US
• Jacques Pappo · Cambridge, US
• Farshad Guirakhoo · Atlanta, US
• Richard D. E. Nichols · Fallbrook, US
• Thomas P. Monath · Harvard, US
• Polly Roy · London, GB

Key dates

• Filing date: Oct 5, 1993
• Grant date: Nov 25, 1997
• Expiry date: Oct 5, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2720/12022
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Method of inducing a mucosal and or/systemic immune response in a host, comprising the step of administering to the host an effective amount of a Bluetongue antigen in the form of virus like and/or virus core like particles. Vaccines are also provided.