Prostaglandin derivatives
US5690957A · kind A · utility
1Cited by
0References
12Claims
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Assignee
Inventors
Key dates
| Filing date | Aug 14, 1996 |
| Grant date | Nov 25, 1997 |
| Priority date | — |
| Expiry date | Aug 14, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08B37/0015
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Prostaglandin E, ester derivatives of the formula (I): ##STR1## wherein R is (i) --CH.sub.2 CH.sub.2 --O--CO--R.sup.1 PA1 (ii) --CH.sub.2 CH.sub.2 --O--CO--CH.sub.2 --O--R.sup.2, and PA1 R.sup.1 and R.sup.2 each independently is C10-20 alkyl; and cyclodextrin clathrates thereof, liposome formulations containing them, and pharmaceutical compositions containing them as active ingredient. The compounds of formula (I) have the effect of increasing blood flow and are useful for the prevention and/or treatment of peripheral circulatory disorder, decubitus, or skin ulcers, or for the maintenance of blood flow.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.