Method for inactivating pathogens in red cell compositions using quinacrine mustard
US5691132A · kind A · utility
58Cited by
4References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 14, 1994 |
| Grant date | Nov 25, 1997 |
| Priority date | — |
| Expiry date | Nov 14, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2795/18163
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and compositions for treating pathogens in material are described, including methods of decontaminating human fluids prior to processing in the clinical laboratory and methods for decontaminating blood products prior to in vivo use. The techniques handle large volumes of human serum without impairing the testing results. Novel compounds for photodecontaminating biological material are also contemplated which are compatible with clinical testing, in that they do not interfere with serum analytes. In particular, quinacrine mustard is used to inactivate pathogens in red cell compositions with retention of red cell function.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.