Patent · US Expired

Immunoglobulin superantigen binding to gp 120 from HIV

US5691135A · kind A · utility

10Cited by

0References

3Claims

0Family size

Assignee

The Regents of the University of California · US

Inventors

Jonathan Braun · Calabasas, US
Lee Goodglick · Los Angeles, US

Key dates

Filing date	Sep 14, 1994
Grant date	Nov 25, 1997
Priority date	—
Expiry date	Sep 14, 2014

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S435/974
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

VH3 and VH4 type immunoglobulins display superantigen-type binding affinity for the HIV gp120 envelope glycoprotein. VH3 and VH4 type antibody molecules, including IgG and IgM, are shown to suppress HIV infection in vivo and in vitro. Determining the level of such antibody molecules is correlated to the advancement of HIV disease state.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.