Method of inhibiting cell growth with the P.sub.2U receptor

US5691156A · kind A · utility

Assignees

• The University of North Carolina at Chapel Hill · US
• The Curators of the University of Missouri · US

Inventors

• Richard C. Boucher, Jr. · Chapel Hill, US
• Gary A. Weisman · Columbia, US
• John T. Turner · Ashland, US
• Thomas K. Harden · Westfield, US
• Claude E. Parr · Chapel Hill, US
• Daniel M. Sullivan · Lutz, US
• Laura J. Erb · Columbia, US
• Kevin D. Lustig · Cambridge, US

Key dates

• Filing date: May 19, 1995
• Grant date: Nov 25, 1997
• Expiry date: May 19, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Isolated DNAs encoding the human P.sub.2U receptor are disclosed, along with vectors and host cells containing the same and methods of using the same. Host cells which are essentially free of endogenous P.sub.2U receptor expression, and which express a heterologous P.sub.2U receptor such as a murine P.sub.2U receptor, are also disclosed, along with methods of using the same.