Lactic acid bacterial suppressor mutants and their use as selective markers and as means of containment in lactic acid bacteria

US5691185A · kind A · utility

Assignee

• Chr. Hansen A/S · DK

Inventors

• Françoise Dickely · Molsheim, FR
• Eric Johansen · Newark, US
• Dan Nilsson · Humlebæk, DK
• Egon Bech Hansen · Hjørring, DK
• Per Str.o slashed.man · Hadsten, DK

Key dates

• Filing date: May 13, 1994
• Grant date: Nov 25, 1997
• Expiry date: May 13, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N15/746
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Useful mutants of lactic acid bacteria or plasmids capable of replicating in lactic acid bacteria, comprising nonsense mutation suppressor-encoding genes, the use of such suppressor genes for confining a replicon to a specific lactic acid bacterium or to a lactic acid bacterium growing in a particular environment and for controlling the number of lactic acid bacterial cells in a particular environment.