Patent · US Expired

Filariid cysteine protease genes

US5691186A · kind A · utility

1Cited by
2References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 5, 1995
Grant dateNov 25, 1997
Priority date
Expiry dateJun 5, 2015

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to parasite astacin metalloendopeptidase and filariid cysteine protease proteins, nucleic acid molecules having sequences that encode such proteins, antibodies raised against such proteins and compounds that can inhibit the activities of parasite astacin metalloendopeptidases or cysteine proteases. The present invention also includes methods to obtain such nucleic acid molecules, proteins, antibodies and inhibitors. The present invention also includes therapeutic compositions comprising such nucleic acid molecules, proteins, antibodies and inhibitors as well as their use to protect animals from disease caused by parasites, such as heartworm.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.