Saccharomyces cerevisiae expressing M.sub.2 protein of influenza A virus
US5691189A · kind A · utility
4Cited by
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10Claims
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Key dates
| Filing date | Nov 9, 1995 |
| Grant date | Nov 25, 1997 |
| Priority date | — |
| Expiry date | Nov 9, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/16122
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A modified Saccharomyces cerevisiae cell, wherein the cell expresses the Influenza virus ion channel protein M.sub.2. Also disclosed is a process for detecting modulators of M.sub.2, which comprises (a) treating such modified Saccharomyces cerevisiae cells with a test substance, and (b) assessing growth in the presence of a test substance, wherein a change in growth signals that the test substance is an M.sub.2 modulator. M.sub.2 inhibitors are useful anti-viral agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.