Methods for coating invasive devices with inhibitors of thrombin
US5691311A · kind A · utility
33Cited by
2References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 11, 1995 |
| Grant date | Nov 25, 1997 |
| Priority date | — |
| Expiry date | May 11, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S623/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to novel biologically active molecules which bind to and inhibit thrombin. Specifically, these molecules are characterized by a thrombin anion-binding exosite association moiety (ABEAM); a linker portion of at least 18 .ANG. in length; and a thrombin catalytic site-directed moiety (CSDM). This invention also relates to compositions, combinations and methods which employ these molecules for therapeutic, prophylactic and diagnostic purposes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.