Heterocyclylcarbonyl substituted benzofuranyl- and -thiophenyl-alkanecarboxyclic acid derivatives

US5691359A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Rüdiger Fischer · Pulheim, DE
• Gabriele Braunlich · Wuppertal, DE
• Mazen Es-Sayed · Langenfeld, DE
• Rudolf Hanko · Düsseldorf, DE
• Stephen Tudhope · Windsor, GB
• Graham Sturton · Maidenhead, GB
• Trevor S. Abram · Marlow, GB
• Mary F. Fitzgerald · Yarnton, GB

Key dates

• Filing date: May 23, 1995
• Grant date: Nov 25, 1997
• Expiry date: May 23, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Heterocyclylcarbonyl substituted benzofuranyl- and thiophenyl-alkanecarboxylic acid derivatives are prepared by reacting appropriately substituted hydroxybenzene butanoic acid esters with heterocyclic ketones. The inventive compounds can be used for the preparation of medicaments, particularly of medicaments for the treatment and prevention of acute and chronic inflammatory processes.