Affinity bound collagen matrices for the delivery of biologically active agents
US5693341A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 16, 1995 |
| Grant date | Dec 2, 1997 |
| Priority date | — |
| Expiry date | Mar 16, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/6435
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Affinity bound collagen matrices for the delivery of biologically active agents, and methods for preparing such matrices, are disclosed. A preferred method for preparing the matrices of the invention comprises mixing a binding ligand and an active agent together, allowing the resulting binding ligand-active agent mixture to form an affinity bound complex, then combining the resulting affinity bound complex with collagen to form a matrix. Particular affinity bound matrices comprising collagen, heparin, and an active agent are also disclosed, as well as methods for using the matrices of the invention for delivery of biologically active agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.