Allergens of alder pollen and applications thereof

US5693495A · kind A · utility

Assignee

• Biomay Produktions-Und Handelsgesellschaft m.b.H. · AT

Inventors

• Heimo Breiteneder · Wien, AT
• Rudolf Valenta · Theresienfeld, AT
• Michael Breitenbach · Wien, AT
• Dietrich Kraft · Wien, AT
• Helmut Rumpold · Wien, AT
• Otto Scheiner · Perchtoldsdorf, AT

Key dates

• Filing date: Jun 1, 1992
• Grant date: Dec 2, 1997
• Expiry date: Jun 1, 2012

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K39/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention provides recombinant DNA molecules which code for polypeptides that exhibit the antigenicity of an Aln g I allergen of alder, Alnus sp., of a Cor a I allergen of hazel or of a Bet v I allergen of birch and other plants of the order Fageles, and for polypeptides comprising at least one epitope thereof, as well as nucleic acids which under stringent conditions hybridize with such DNA sequences or are derivable from such sequences by degeneracy of the genetic code. In addition, methods are described for using the polypeptides coded by these DNA molecules and their use in the diagnosis or therapy of allergic diseases.