4-(Quinolin-2-yl-methoxy)-phenyl-acetic acid derivatives

US5693650A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Ulrich Muller · Wuppertal, DE
• Richard Connell · Trumbull, US
• Siegfried Goldmann · Wuppertal, DE
• Klaus-Helmut Mohrs · Wuppertal, DE
• Rolf Angerbauer · Wuppertal, DE
• Matthias Muller-Gliemann · Haan, DE
• Ulrich Niewohner · Wermelskirchen, DE
• Rudi Grutzmann · Solingen, DE
• Martin Beuck · Milford, US
• Stefan Wohlfeil · Hilden, DE
• Hilmar Bischoff · Wuppertal, DE
• Dirk Denzer · Wuppertal, DE

Key dates

• Filing date: Dec 5, 1995
• Grant date: Dec 2, 1997
• Expiry date: Dec 5, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H13/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

4-(Quinolin-2-yl-methoxy)-phenyl-acetic acid derivatives are prepared by reacting quinoline-methoxy-phenyl-acetic acids with the corresponding glycinol derivatives, if appropriate with activation of the carboxylic acid function. The new compounds are suitable as active compounds in medicaments, in particular in antiatherosclerotic medicaments.