3,4,5-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic and medicament containing them

US5693672A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Andreas Weichert · Egelsbach, DE
• Hans-Jochen Lang · Hofheim, DE
• Wolfgang Scholz · Beverly, US
• Udo Albus · Florstadt, DE
• Florian Lang · Gilching, DE

Key dates

• Filing date: May 26, 1995
• Grant date: Dec 2, 1997
• Expiry date: May 26, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

3,4,5-Substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic and medicament containing them Benzoylguanidines of the formula I ##STR1## where R(1) is R(4)--SO.sub.m or R(5)R(6)N--SO.sub.2 --, where R(4) and R(5) are alk(en)yl, --C.sub.n H.sub.2n --R(7), and where R(7) is cycloalkyl or phenyl, where R(5) is also H, R(6) is H or C.sub.1 --C.sub.4 --alkyl, R(2) is hydrogen, (cyclo)-alk(en)(yn)yl, aryl and hetaryl, R(3) is defined as R(2) and their pharmaceutically tolerable salts are described.