Unsaturated carbohydrate derivatives polymers thereof and their use

US5693768A · kind A · utility

Assignee

• CIBA Vision Corporation · US

Inventors

• Frank Bachmann · Glückstadt, DE
• Dieter Lohmann · Münchenstein, CH
• Peter Chabrecek · Clayton, AU

Key dates

• Filing date: Feb 13, 1995
• Grant date: Dec 2, 1997
• Expiry date: Feb 13, 2015

Classification

• Technology area (CPC G): Physics
• CPC primary: G02B1/043
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to polymerisable derivatives of carbohydrates comprising a compound of formula (I) EQU R.sup.1 --(COO--Alk).sub.m -(OCONH--R).sub.n -(NHCO).sub.p Y--Z (I) wherein R.sup.1 is a radically polymerisable hydrocarbon group; m, n and p are 0 or 1; Alk is alkylene having up to 10 carbon atoms; R is a diradical, having up to 20 carbon atoms, of an organic diisocyanate; Z is a monovalent radical, minus a single hydroxy group, of a mono-, di- or tri-saccharide, of an oligosaccharide, of a cyclodextrin (CD) or of an anhydrosaccharide; and Y is --O-- or --NH--; with the proviso that when p is zero, m and n are also zero and Y is --NH--; to homopolymers, copolymers, block copolymers, graft copolymers and polymeric networks thereof, to moulded articles, for example contact lenses or biomedicinal articles, comprising the mentioned polymers, as well as to processes for the preparation of the mentioned polymers and articles.