Glycosylated steroid derivatives for transport across biological membranes and process for making and using same
US5693769A · kind A · utility
44Cited by
26References
6Claims
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Key dates
| Filing date | Apr 20, 1994 |
| Grant date | Dec 2, 1997 |
| Priority date | — |
| Expiry date | Apr 20, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/3515
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel glycosylated steroid derivatives for facilitating the transport of compounds across biological membranes, either in admixture or as conjugates, are disclosed. A novel process for efficient synthesis of these glycosylated steroid derivatives, using activated glycosyl sulfoxide intermediates is provided. Methods for the permeabilization of membranes and the enhancement of the activity of predetermined compounds are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.