Substituted 4-aza-5.alpha.-androstan-ones as 5.alpha.-reductase inhibitors

US5693809A · kind A · utility

Assignee

• MERCK & CO., INC. · US

Inventors

• Philippe L. Durette · New Providence, US
• William K. Hagmann · Westfield, US
• Gary H. Rasmusson · Watchung, US
• Richard L. Tolman · Hackettstown, US
• Ihor E. Kopka · Hampton, US
• Soumya P. Sahoo · Old Bridge, US
• Craig K. Esser · Belford, US
• Nathan G. Steinberg · Boca Raton, US
• Donald W. Graham · Mountainside, US
• Bruce E. Witzel · Westfield, US

Key dates

• Filing date: May 12, 1995
• Grant date: Dec 2, 1997
• Expiry date: May 12, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07J73/005
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Described are new 16-substituted and 7,16-disubstituted 4-aza-5.alpha.-androstan-3-ones and related compounds as 5.alpha.-reductase inhibitors.