Dimeric DTPA derivatives, their metal complexes and pharmaceutical agents containing these complexes

US5695737A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Werner Krause · Plantsville, US
• Franz-Karl Maier · Berlin, DE
• Michael Bauer · Berlin, DE
• Gabriele Schuhmann-Giampieri · Berlin, DE
• Wolf-Rudiger Press · Berlin, DE
• Johannes Platzek · Berlin, DE
• Heribert Schmitt-Willich · Berlin, DE

Key dates

• Filing date: Jun 7, 1995
• Grant date: Dec 9, 1997
• Expiry date: Jun 7, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C237/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to new dimeric DTPA derivatives, their metal complexes, containing at least one ion of an element of atomic numbers 21-32, 37-39, 42-51 and 57-83, agents containing these complexes, their use in NMR diagnosis and/or diagnostic radiology, radiodiagnosis and radiotherapy, as well as process for their production.