Method for producing Leu.sup.13 !motilin
US5695952A · kind A · utility
1Cited by
2References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 25, 1995 |
| Grant date | Dec 9, 1997 |
| Priority date | — |
| Expiry date | May 25, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/75
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel motilin analog peptide containing leucine instead of the usual 13th amino acid methionine, as in the naturally occurring motilin, is produced by gene recombination techniques in which several or identical genes, each coding for the novel peptide, are joined in series into a vector. The resultant recombinant DNA is introduced into Escherichia coli and the resultant transformant is cultivated. The resulting polymeric peptide can be cleaved to give the desired peptide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.