Recombinant DNA vectors, including plasmids, and host cells for production of truncated thrombomodulin
US5695964A · kind A · utility
11Cited by
6References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 17, 1996 |
| Grant date | Dec 9, 1997 |
| Priority date | — |
| Expiry date | Jan 17, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to novel vectors and host cells containing nucleic acids coding for a polypeptide having thrombin binding ability, anticoagulant activity and thrombolytic activity. The polypeptide can be efficiently produced in large quantities by means of genetic recombination techniques using the vectors and host cells of the present invention. Since the polypeptide exhibits anticoagulant activity and thrombolytic activity without generating side effects such as bleeding tendencies, it can be applied effectively to the prevention and treatment of hypercoagulability-related diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.