Targeted delivery of virus vector to mammalian cells

US5695991A · kind A · utility

Assignee

• Got-A-Gene AB · SE

Inventors

• Leif Lindholm · Handen, SE
• Sven Enerback · Mölndal, SE
• Orjan Strannegård · Mölndal, SE

Key dates

• Filing date: Jun 17, 1994
• Grant date: Dec 9, 1997
• Expiry date: Jun 17, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N15/64
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A complex between a virus the cell binding receptor of which has been inactivated and an antibody, said antibody having the ability to interact with a specific antigen on the surface of a mammalian cell different from the cellular structure which would otherwise mediate binding of the virus to the cell surface and which antigen has the ability to mediate entrance of a virus vector or infectious virus into mammalian cells.