Azaheterocyclymethyl-chromans

US5696137A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Hans-Georg Heine · Krefeld, DE
• Rudolf Schohe-Loop · Wuppertal, DE
• Thomas Glaser · Overath, DE
• Jean De Vry · Stolberg, DE
• Wolfgang Dompert · Cologne, DE
• Henning Sommermeyer · Neunburg vorm Wald, DE

Key dates

• Filing date: Jun 2, 1995
• Grant date: Dec 9, 1997
• Expiry date: Jun 2, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D513/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Azaheterocyclylmethyl-chromans of the formula: ##STR1## in which E represents an azaheterocyclyl group selected from the group consisting of: ##STR2## wherein R.sup.6 represents hydrogen, hydroxyl, halogen or phenyl; and PA1 n represents an integer 0-8; and the other substituents are as defined herein; or an optically isomeric form thereof or a salt thereof; are useful to treat anxiety, depression and psychoses.