Patent · US Expired

Composition of s(-) sodium ibuprofen

US5696165A · kind A · utility

10Cited by

28References

15Claims

0Family size

Assignee

THE BOOTS COMPANY PLC · GB

Inventors

Bernard John Armitage
John F. Lampard · Mansfield, GB
Alan Smith · Grafton, GB

Key dates

Filing date	Nov 14, 1995
Grant date	Dec 9, 1997
Priority date	—
Expiry date	Nov 14, 2015

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C57/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The use of S(-)sodium 2-(4-isobutylphenyl)propionate (the sodium salt of S(+)-ibuprofen) in pharmaceutical compositions for the treatment of inflammation, pain and pyrexia is described. Preferred compositions comprise S(-)sodium 2-(4-isobutylphenyl)propionate dihydrate. Processes to prepare S(-)sodium 2-(4-isobutyl-phenyl)propionate and its use in a process to prepare S(+) 2-(4-isobutylphenyl)propionic acid of high enantiomeric purity are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.