Polyspecific immunoconjugates and antibody composites for targeting the multidrug resistant phenotype
US5698178A · kind A · utility
98Cited by
3References
24Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 8, 1996 |
| Grant date | Dec 16, 1997 |
| Priority date | — |
| Expiry date | Apr 8, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/31
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Polyspecific immunoconjugates and antibody composites that bind a multidrug transporter protein and an antigen associated with a tumor or infectious agent are used to overcome the multidrug resistant phenotype. These immunoconjugates and composites also can be used diagnostically to determine whether the failure of traditional chemotherapy is due to the presence of multidrug resistant tumor cells, multidrug resistant HIV-infected cells or multidrug resistant infectious agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.