Patent · US Expired

Transdermal therapeutic system for the administration of physostigmine to the skin and process for the production thereof

US5698216A · kind A · utility

0Cited by

2References

9Claims

0Family size

Assignee

LTS Lohmann Therapie-Systeme AG · DE

Inventors

Lothar Deurer · Koblenz, DE
Thomas Hille · Neuwied, DE
Thomas Profitlich · Munich, DE
Fritz Stanislaus · Munich, DE
Kersten Walter · Munich, DE

Key dates

Filing date	Jul 12, 1995
Grant date	Dec 16, 1997
Priority date	—
Expiry date	Jul 12, 2015

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P25/28
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A transdermal therapeutic system for the administration of physostigmine to the skin, consisting of a backing layer impermeable to active substance, a pressure-sensitive reservoir layer containing 40 to 90%-wt. polymeric material and 0.1 to 20%-wt. physostigmine base or one of the pharmaceutically acceptable salts thereof, and of a detachable protective layer covering the reservoir layer, comprises in its reservoir layer acrylate- and/or methacrylate-based polymeric material and 0.1 to 40%-wt. of a softener containing the hydroxyl group with an HLB value between 1.1 and 12.0.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.