Patent · US Expired

Method for measuring antigens or antibodies in biological fluids

US5698450A · kind A · utility

106Cited by
14References
9Claims
0Family size

Inventors

Key dates

Filing dateSep 22, 1995
Grant dateDec 16, 1997
Priority date
Expiry dateSep 22, 2015

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/115831
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The invention relates to a method of measuring antigens or antibodies in biological fluids in appropriately designed reaction cells in an automated analytical apparatus. The method includes the steps of contacting, in the reaction cell, the biological fluid with antibodies specific for a desired analyte antigen, which antibodies are coated on magnetic particulate carrier, under conditions such that binding of the antibody to the desired analyte antigen occurs, and detecting the presence or absence of an immunocomplex formed between the antibody and the desired analyte antigen. The automated analytical apparatus includes a closed circuit transfer path having means for transferring cells around the entire transfer path, and a thermostating period for each analysis to be performed with the automated analytical apparatus. The transfer path includes a loading station, a reagent delivery station, a mixing and washing station, a separating station and a discharging station. A specific code is placed on each cell for identifying a kind of analysis to be effected with respect to that cell.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.