Transdermal drug delivery process
US5700481A · kind A · utility
18Cited by
2References
26Claims
0Family size
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Inventors
Key dates
| Filing date | Mar 12, 1996 |
| Grant date | Dec 23, 1997 |
| Priority date | — |
| Expiry date | Mar 12, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/0448
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A calcitonin, its derivative or a salt thereof is transdermally delivered by iontophoresis in which a substantially constant voltage in the range of 3 to 20 V is applied at an electric current of 0.05 to 0.5 mA/cm.sup.2. In this process, the calcitonin can be delivered transdermally with a higher absorptivity by applying a higher voltage for a short period (at a voltage of about 6 to 14 V for about 5 to 15 minutes) in the initial stage of the voltage application, and then applying a lower voltage for a long period (at a voltage of about 3 to 9 V for about 30 to 40 minutes).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.