Hydrogels of absorbable polyoxaesters containing amines or amido groups
US5700583A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 6, 1996 |
| Grant date | Dec 23, 1997 |
| Priority date | — |
| Expiry date | Nov 6, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T442/56
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention describes a crosslinked aliphatic polyoxaesters containing amines and/or amido groups and blends thereof with other polymers that may be used to produce surgical devices such as sutures, sutures with attached needles, molded devices, and the like. The crosslinked aliphatic polyoxaesters of the present invention is formed from an aliphatic polyoxaester having a first divalent repeating unit of formula I: EQU O--C(O)--C(R.sub.1)(R.sub.2)--O--(R.sub.3)--O--C(R.sub.1)(R.sub.2)--C(O)-- !I and a second repeating unit of the formula: EQU --O--R.sub.12 --!.sub.U, XVI and optionally a third repeating unit with a formula selected from the group consisting of: EQU --O--R.sub.4 --!.sub.A, II EQU --O--R.sub.5 --C(O)--!.sub.B, III EQU (--O--R.sub.5 --C(O)!.sub.P --O--).sub.L G XI and combinations thereof wherein R.sub.12 contains an internal amine or internal amide group wherein the aliphatic polyoxaester has been crosslinked.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.