HIV-1 gag cytotoxic T-lymphocyte epitope and method of use
US5700635A · kind A · utility
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7Claims
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Key dates
| Filing date | Dec 19, 1994 |
| Grant date | Dec 23, 1997 |
| Priority date | — |
| Expiry date | Dec 19, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16222
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel human immunodeficiency virus type 1 (HIV-1) cytotoxic T-lymphocyte (CTL) epitope has been identified in the gag coding region. This epitope corresponds to amino acids 255-269 of Gag and has the following sequence: NH.sub.2 -asn-pro-pro-ile-pro-val-gly-glu-ile-tyr-lys-arg-trp-ile-ile-COOH. This peptide interacts specifically with human leukocyte antigen-B8 (HLA-B8). This peptide is useful for the identification HIV-1 gag-specific CTL.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.