Method for producing optically active ester of .gamma.-substituted-.beta.-hydroxybutyric acid
US5700670A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 10, 1996 |
| Grant date | Dec 23, 1997 |
| Priority date | — |
| Expiry date | Apr 10, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/911
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Microbial cells and/or a preparation therefrom of a microorganism is allowed to act on an ester of .gamma.-substituted-acetoacetic acid, and a carbonyl group at its .beta.-position is stereospecifically reduced, wherein the microorganism is selected from the group consisting of those belonging to the genera Yarrowia, Filobasidium, Metschnikowia, Galactomyces, Ambrosiozyma, Trichosporonoides, Aureobasidium, Phaeococcomyces, Rosulomyces, Dothichiza, Emericellopsis, Calonectria, Colletotrichum, and Ceratocystis, preferably, the microorganism is microorganism belonging to the genus Aureobasidium. Thus an optically active ester of .gamma.-substituted-.beta.-hydroxybutyric acid having a high optical purity is produced in a short period of time at a high accumulated concentration and a high yield.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.