Methods of making transgenic animals producing oligosaccharides and glycoproteins
US5700671A · kind A · utility
50Cited by
5References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 2, 1995 |
| Grant date | Dec 23, 1997 |
| Priority date | — |
| Expiry date | May 2, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2267/01
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to transgenic non-human mammals characterized in that the genome of said mammals contain at least one heterologous gene encoding for the production of heterologous catalytic entity selected from the group consisting of enzymes and antibodies, and wherein said catalytic entity produces a second heterologous product in the milk of said mammal. Especially useful in the practice of the invention are human glycosyltransferases and transgenic sheep, goats and cows. The heterologous product includes oligosaccharides and glycoconjugates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.