Lipid vesicles having a bilayer containing a surfactant with anti-viral and spermicidal activity
US5700679A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jun 7, 1996 |
| Grant date | Dec 23, 1997 |
| Priority date | — |
| Expiry date | Jun 7, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S424/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel formulation having anti-viral and spermicidal properties has been developed. The formulation contains lipid vesicles having an outer bilayer formed of a non-ionic amphiphile, a surfactant such as having spermicidal and/or anti-viral activity, an oil and a sterol. The selection of the components making the vesicle is such that the formulation provides rapid spermicidal or anti-viral activity. The formulation and methods of the invention are particularly useful in the mucous membranes such as the vaginal tract and has been tested against viruses such as HIV and Vaccinia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.