Method for the preparation of in vitro-derived human neutrophil precursor cells
US5700691A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 13, 1996 |
| Grant date | Dec 23, 1997 |
| Priority date | — |
| Expiry date | Sep 13, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/39
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A composition of human neutrophil precursor cells is disclosed wherein at least 16% of the cells are human myeloblasts and promyelocytes. The myeloblasts and promyelocytes are derived from human neutrophil progenitor cells that were obtained from peripheral blood, bone marrow or cord blood. The neutrophil precursor cells contain less than 5% colony forming units. Also disclosed are human neutrophil precursor cells made up of about 16% CD15+CD11b- cells and less than 5% colony forming units and methods of preparing these compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.