Patent · US Expired

3'-deoxy or 3'-O-substituted-2',5'-oligoadenylates as antiviral agents

US5700785A · kind A · utility

14Cited by

8References

37Claims

0Family size

Assignee

Temple University-Of The Commonwealth System of Higher Education · US

Inventors

Robert J. Suhadolnik · Roslyn, US
Wolfgang Pfleiderer · Konstanz, DE

Key dates

Filing date	Mar 14, 1994
Grant date	Dec 23, 1997
Priority date	—
Expiry date	Mar 14, 2014

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07H23/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Synthetic analogs of 2',5'-oligoadenylate wherein the aglycon, ribosyl moiety and/or terminal nucleoside have been modified are effective therapeutic agents, particularly against HIV infection. The analogs are utilized in compositions and methods for the treatment of disorders characterized by 2-5A pathway defects.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.